Immunocytochemistry of neuron specific enolase (NSE) in the rat brain after single and repeated epileptic seizures.

نویسندگان

  • Melda Yardimoğlu
  • Gul Ilbay
  • Cannur Dalcik
  • Hakki Dalcik
  • Deniz Sahin
  • Nurbay Ates
چکیده

The aim of this study was to investigate neuron-specific enolase (NSE) immunoreactivity of the different brain regions after pentylenetetrazol (PTZ)- induced epileptic seizures in rats. Light microscopic examinations provided evidences for changes of neuronal activity after single and repeated seizures. The number of NSE (+) cells was well correlated with Nissl staining. The results suggest that NSE immunoreactivity may be a valuable marker for determination of the number of metabolically active neurons in different brain regions after single and repeated experimental seizures.

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عنوان ژورنال:
  • The International journal of neuroscience

دوره 118 7  شماره 

صفحات  -

تاریخ انتشار 2008